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Invitrogen
ARHGEF4 Monoclonal Antibody (ARHGEF-08)
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Product Details
MA5-28622
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
ARHGEF-08
Immunogen
Recombinant fragment of human ARHGEF4 (amino acids 143-271)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
15mM sodium azide
Storage conditions
4°C, do not freeze
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody recognizes human intracellular protein ARHGEF4 / ASEF1, approx. 80 kDa guanine nucleotide exchange factor specific for Rac1 and Cdc42. The epitope is located in the rough at the region of SH3 domain.
Target Information
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. This protein is similar to rat collybistin protein. Alternative splicing of this gene generates two transcript variants which encode different isoforms. Also there is possibility for the usage of multiple polyadenylation sites for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: APC-stimulated guanine nucleotide exchange factor 1; ARHGEF4; Asef; DKFZp434G2016; Rho guanine nucleotide exchange factor (GEF) 4; Rho guanine nucleotide exchange factor 4
Gene Aliases: ARHGEF4; ASEF; ASEF1; GEF4; KIAA1112; SMIM39; STM6
UniProt ID: (Human) Q9NR80
Entrez Gene ID: (Human) 50649
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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