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Invitrogen
DGCR8 Recombinant Rabbit Monoclonal Antibody (ST04-79)
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Product Details
MA5-32153
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
ST04-79
Immunogen
Recombinant protein within Human DGCR8 aa 383-773.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
TBS, pH 7.4, with 40% Glycerol, 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
Target Information
This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein, Drosha. Alternate splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DiGeorge syndrome critical region 8; DiGeorge syndrome critical region 8 homolog; DiGeorge syndrome critical region gene 8; Em:AC006547.4; Gy1; Microprocessor complex subunit DGCR8; unnamed protein product
Gene Aliases: C22orf12; D16H22S1742E; D16H22S788E; D16Wis2; DGCR8; DGCRK6; Gy1; LP4941; mir-1306; N41; pasha; Vo59c07
UniProt ID: (Human) Q8WYQ5, (Mouse) Q9EQM6
Entrez Gene ID: (Human) 54487, (Mouse) 94223, (Rat) 287954
RNA binding
double-stranded RNA binding
protein binding
heme binding
protein binding, bridging
identical protein binding
protein homodimerization activity
metal ion binding
primary miRNA binding
protein-RNA adaptor activity
ribonuclease III activity
molecular_function
RNA processing factor
scaffold/adaptor protein
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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