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FIGURE: 1 / 15
Moesin Antibody (MA5-32231) in ICC/IF
Immunocytochemical analysis of Moesin in NCCIT cells using a Moesin Monoclonal antibody (Product # MA5-32231) as seen in green. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Product Details
MA5-32231
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
SC69-01
Immunogen
Synthetic peptide within Human Moesin aa 455-500.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
TBS, pH 7.4, with 40% Glycerol, 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
Target Information
Moesin, a member of the talin-4. 1 superfamily, is a linking protein of the submembraneous actin cytoskeleton. It is expressed in macrophages, lymphocytes, fibroblastic, endothelial, epithelial, and neuronal cell lines but not in blood cells. It is involved in cell adhesion, migration, and organization of cell surface structures.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: epididymis luminal protein 70; Membrane-organizing extension spike protein; Moesin; unnamed protein product
Gene Aliases: C78546; HEL70; IMD50; MSN
UniProt ID: (Human) P26038, (Rat) O35763, (Mouse) P26041
Entrez Gene ID: (Human) 4478, (Rat) 81521, (Mouse) 17698
immunological synapse formation
cytoskeleton organization
leukocyte cell-cell adhesion
regulation of cell shape
regulation of cell size
positive regulation of gene expression
gland morphogenesis
membrane to membrane docking
T cell proliferation
establishment of epithelial cell apical/basal polarity
positive regulation of protein catabolic process
leukocyte migration
establishment of endothelial barrier
T cell aggregation
positive regulation of podosome assembly
T cell migration
regulation of organelle assembly
positive regulation of protein localization to early endosome
regulation of lymphocyte migration
positive regulation of early endosome to late endosome transport
positive regulation of cellular protein catabolic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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