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Invitrogen
H-cadherin Recombinant Rabbit Monoclonal Antibody (JB14-48)
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Product Details
MA5-34710
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
JB14-48
Immunogen
Recombinant protein within Human H Cadherin aa 81-220.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
TBS, pH 7.4, with 40% glycerol, 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles, store in dark
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Control: Rat skeletal muscle tissue, human kidney tissue, human fetal skeletal muscle tissue, mouse heart tissue.
Target Information
The protein encoded by this gene has a C-terminal domain with tRNA 3 processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CAD13; cadherin 13, H-cadherin (heart); Cadherin-13; CD39 antigen-like 3; CD39-like 3; CD39L3; ecto-apyrase 3; ecto-ATPase 3; ecto-ATPDase 3; H-cadherin; H-cadherin (heart); HB6; Heart cadherin; heart-cadherin; NTPDase 3; NTPDase-3; P105; T cad; T Cadherin; T-cad; T-cadherin; Truncated cadherin; truncated-cadherin; unnamed protein product
Gene Aliases: CDH13; CDHH; P105
UniProt ID: (Human) P55290
Entrez Gene ID: (Human) 1012
cell morphogenesis
positive regulation of endothelial cell proliferation
positive regulation of cell-matrix adhesion
sprouting angiogenesis
cell-cell junction assembly
cell adhesion
homophilic cell adhesion via plasma membrane adhesion molecules
negative regulation of cell adhesion
Rho protein signal transduction
negative regulation of cell proliferation
calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
cell migration
Rac protein signal transduction
lamellipodium assembly
regulation of endocytosis
positive regulation of cell migration
adherens junction organization
regulation of epidermal growth factor receptor signaling pathway
endothelial cell migration
keratinocyte proliferation
cell-cell adhesion mediated by cadherin
positive regulation of transcription from RNA polymerase II promoter
positive regulation of smooth muscle cell proliferation
positive regulation of calcium-mediated signaling
positive regulation of positive chemotaxis
regulation of transport
localization within membrane
low-density lipoprotein particle mediated signaling
cellular response to xenobiotic stimulus
cellular response to toxic substance
cell-cell adhesion
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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