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Invitrogen
CK2 beta Recombinant Rabbit Monoclonal Antibody (9T5J10)
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Product Details
MA5-35525
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
9T5J10
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 101-215 of human Casein Kinase 2 beta (CSNK2B) (CSNK2B) (P67870)
Conjugate
Form
Liquid
Concentration
0.28 mg/mL
Amount
28 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: YQQGDFGYCP RVYCENQPML PIGLSDIPGE AMVKLYCPKC MDVYTPKSSR HHHTDGAYFG TGFPHMLFMV HPEYRPKRPA NQFVPRLYGF KIHPMAYQLQ LQAASNFKSP VKTIR
Target Information
This gene encodes the beta subunit of casein kinase II, a ubiquitous protein kinase which regulates metabolic pathways, signal transduction, transcription, translation, and replication. The enzyme is composed of three subunits, alpha, alpha prime and beta, which form a tetrameric holoenzyme. The alpha and alpha prime subunits are catalytic, while the beta subunit serves regulatory functions. The enzyme localizes to the endoplasmic reticulum and the Golgi apparatus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alternative name: G5a, phosvitin; casein kinase 2, beta polypeptide; casein kinase 2, beta subunit; Casein kinase II beta subunit; Casein kinase II subunit beta; chimera Csnk2b-Ly6g5b splicing isoform 2050; chimera Csnk2b-Ly6g5b splicing isoform 2275; chimera Csnk2b-Ly6g5b splicing isoform 2531; chimera Csnk2b-Ly6g5b splicing isoform 901; CK II beta; CSNK2B; Csnk2b splicing isoform 280; Csnk2b splicing isoform 662; Csnk2b-Ly6g5b; CSNK2B-LY6G5B-1072; CSNK2B-LY6G5B-1103; CSNK2B-LY6G5B-532; CSNK2B-LY6G5B-560; CSNK2B-LY6G5B-562; DADB-127H9.2; MGC138222; MGC138224; Phosvitin; Protein G5a; protein kinase; unnamed protein product
Gene Aliases: CK II beta; Ck2; CK2B; CK2N; Ckb1; Ckb2; CSK2B; CSNK2B; G5A; POBINDS
UniProt ID: (Human) P67870, (Rat) P67874, (Mouse) P67871
Entrez Gene ID: (Human) 1460, (Rat) 81650, (Mouse) 13001
chromatin binding
protein serine/threonine kinase activity
receptor binding
protein binding
protein kinase regulator activity
protein domain specific binding
protein binding, bridging
identical protein binding
metal ion binding
RNA polymerase II sequence-specific DNA binding transcription factor binding
transcription factor binding
kinase modulator
signal transduction
negative regulation of cell proliferation
Wnt signaling pathway
peptidyl-threonine phosphorylation
release from viral latency
negative regulation of proteasomal ubiquitin-dependent protein catabolic process
positive regulation of activin receptor signaling pathway
adiponectin-activated signaling pathway
negative regulation of blood vessel endothelial cell migration
positive regulation of SMAD protein import into nucleus
endothelial tube morphogenesis
protein-containing complex assembly
symbiont-mediated disruption of host cell PML body
negative regulation of viral life cycle
I-kappaB kinase/NF-kappaB signaling
positive regulation of pathway-restricted SMAD protein phosphorylation
positive regulation of Wnt signaling pathway
regulation of protein kinase activity
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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