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Invitrogen
Nectin 2 Recombinant Rabbit Monoclonal Antibody (3H0G2)
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FIGURE: 1 / 5
Nectin 2 Antibody (MA5-35822) in IHC (P)
Immunohistochemistry analysis of Nectin 2 in paraffin-embedded human placenta. Samples were incubated with Nectin 2 Monoclonal antibody (Product # MA5-35822) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
Product Details
MA5-35822
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
3H0G2
Immunogen
Recombinant protein (or fragment)
Conjugate
Form
Liquid
Concentration
0.42 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CD112; Herpes virus entry mediator B; Herpesvirus entry mediator B; herpesvirus entry protein B; HveB; mHveB; Murine herpes virus entry protein B; murine herpesvirus entry protein B; Nectin cell adhesion molecule 2; Nectin-2; Poliovirus receptor homolog; poliovirus receptor related 2; poliovirus receptor-like 2; poliovirus receptor-related 2 (herpesvirus entry mediator B); Poliovirus receptor-related protein 2; poliovirus sensitivity; PVRL2; unnamed protein product
Gene Aliases: AI325026; AI987993; CD112; HVEB; MPH; nectin-2; NECTIN2; PRR2; Pvr; PVRL2; PVRR2; Pvs
UniProt ID: (Human) Q92692, (Mouse) P32507
Entrez Gene ID: (Human) 5819, (Rat) 308417, (Mouse) 19294
acrosome assembly
positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
positive regulation of immunoglobulin mediated immune response
cytoskeleton organization
cell adhesion
homophilic cell adhesion via plasma membrane adhesion molecules
signal transduction
spermatid development
spermatid nucleus differentiation
fertilization
fusion of virus membrane with host plasma membrane
sperm mitochondrion organization
cellular component morphogenesis
positive regulation of mast cell activation
natural killer cell mediated cytotoxicity
susceptibility to natural killer cell mediated cytotoxicity
adhesion of symbiont to host
cilium organization
negative regulation of natural killer cell mediated cytotoxicity
positive regulation of natural killer cell mediated cytotoxicity
regulation of viral entry into host cell
viral entry into host cell
coreceptor-mediated virion attachment to host cell
positive regulation of T cell receptor signaling pathway
establishment of localization in cell
establishment of mitochondrion localization
susceptibility to T cell mediated cytotoxicity
biological_process
cell part morphogenesis
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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