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Phospho-HCLS1 (Tyr397) Recombinant Rabbit Monoclonal Antibody (HS1Y397-F12)
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FIGURE: 1 / 5
Phospho-HCLS1 (Tyr397) Antibody (MA5-37159) in WB
Western blot analysis of Phospho-HS1 (Tyr397) using Ramos cell extract. Samples were untreated or treated with 300 nM Thapsigargin (30 min), and incubated in monoclonal Phospho-HS1 (Tyr397) antibody (Product # MA5-37159) with a dilution of 0.01 µg/mL.
Product Details
MA5-37159
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG, kappa
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
HS1Y397-F12
Immunogen
A synthetic phospho-peptide corresponding to residues surrounding Tyr397 of human phospho HS1.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Protein A/G
Storage buffer
PBS with 50% glycerol, 0.10% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: HCLS1; Hematopoietic cell-specific LYN substrate 1; Hematopoietic lineage cell-specific protein; LckBP1; p75; unnamed protein product
Gene Aliases: AW213261; CTTNL; HCLS1; HS1; lckBP1; p75
UniProt ID: (Human) P14317, (Mouse) P49710
Entrez Gene ID: (Human) 3059, (Mouse) 15163
protein binding
SH3 domain binding
protein kinase binding
signaling adaptor activity
macromolecular complex binding
actin filament binding
RNA polymerase II sequence-specific DNA binding transcription factor binding
RNA polymerase II transcription factor binding
actin binding
protein complex binding
actin or actin-binding cytoskeletal protein
cytoskeletal protein
non-motor actin binding protein
negative regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
actin filament organization
signal transduction
positive regulation of cell proliferation
response to hormone
erythrocyte differentiation
regulation of actin filament polymerization
positive regulation of granulocyte differentiation
intracellular signal transduction
granulocyte colony-stimulating factor signaling pathway
positive regulation of protein import into nucleus
positive regulation of macrophage differentiation
positive regulation of transcription from RNA polymerase II promoter
nuclear transport
positive regulation of protein kinase B signaling
cellular response to cytokine stimulus
negative regulation of leukocyte apoptotic process
positive regulation of phosphatidylinositol 3-kinase signaling
actin filament polymerization
positive regulation of peptidyl-serine phosphorylation
positive regulation of tyrosine phosphorylation of STAT protein
positive regulation of transcription factor import into nucleus
positive regulation of peptidyl-tyrosine phosphorylation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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