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Invitrogen
Collagen III Recombinant Rabbit Monoclonal Antibody (6Y9C6)
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FIGURE: 1 / 3
Collagen III Antibody (MA5-42628) in WB
Western blot analysis of Collagen III in extracts of various cell lines. Samples were incubated with Collagen III Monoclonal antibody (Product # MA5-42628) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.
Product Details
MA5-42628
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
6Y9C6
Immunogen
Recombinant protein (or fragment)
Conjugate
Form
Liquid
Concentration
0.95 mg/mL
Amount
95 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive test controls include: HepG2, RD, SH-SY5Y, Mouse brain, Mouse uterus, Rat lung, Rat uterus. The target is usually found in the following locations: Secreted, extracellular matrix, extracellular space.
Immunogen sequence: NYSPQYDSYD VKSGVAVGGL AGYPGPAGPP GPPGPPGTSG HPGSPGSPGY QGPPGEPGQA GPSGPPGPPG AIGPSGPAGK DGESGRPGRP GERGLPGPPG IKGPAGIPGF PGMKGHRGFD GRNGEKGETG APGLKGENGL PGENGAPGPM GPRGAPGERG RPGLPGAAGA RGNDGARGSD GQPGPPGPPG TAGFPGSPGA KGEVGPAGSP GSNGAPGQRG EPGPQGHAGA QGPPGPPGIN GSPGGKGEMG P
Target Information
Collagen III is a fibrillar collagen that is found in extensible connective tissues such as skin, lung, and the vascular system, frequently in association with type I Collagen. Mutations in th gene are associated with Ehlers Danlos syndrome type IV, and with aortic and arterial aneurysms. Although alternate transcripts have been detected for this gene, they are the result of mutations; these mutations alter splicing, often leading to the exclusion of multiple exons.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alpha-1 type III collagen; alpha-1(III) procollagen; alpha1 (III) collagen; COL 3; COL3; COL3 alpha 1; Collagen 3; Collagen alpha-1(III) chain; collagen, fetal; collagen, type III, alpha 1; Collagen3; Ehlers-Danlos syndrome type IV, autosomal dominant; FLJ34534; MGC93704; minisatellite 10w detected by probe MMS10; procollagen, type III, alpha 1; unnamed protein product
Gene Aliases: AW550625; Col3a-1; COL3A1; EDS4A; EDSVASC; mKIAA4231; MMS10-W; Ms10w; PMGEDSV
UniProt ID: (Human) P02461, (Mouse) P08121, (Rat) P13941
Entrez Gene ID: (Human) 1281, (Mouse) 12825, (Rat) 84032
blood vessel development
in utero embryonic development
neuron migration
tissue homeostasis
chondrocyte differentiation
cell-matrix adhesion
transforming growth factor beta receptor signaling pathway
integrin-mediated signaling pathway
heart development
response to radiation
gene expression
peptide cross-linking
layer formation in cerebral cortex
cerebral cortex development
platelet activation
extracellular matrix organization
collagen fibril organization
lung development
transforming growth factor beta1 production
response to cytokine
positive regulation of Rho protein signal transduction
multicellular organism growth
aorta development
limb joint morphogenesis
wound healing
skin development
fibroblast proliferation
elastic fiber assembly
animal organ development
digestive tract development
system development
negative regulation of immune response
cartilage development
endochondral bone morphogenesis
aorta smooth muscle tissue morphogenesis
cellular response to amino acid stimulus
basement membrane organization
fibril organization
response to angiotensin
negative regulation of neuron migration
extracellular fibril organization
skeletal system development
aging
response to mechanical stimulus
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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