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Invitrogen
Cytokeratin 4/5/6/8/10/13/18 Monoclonal Antibody (C-11)
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Product Details
MA5-43995
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mammal
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
C-11
Immunogen
Keratin-enriched preparation from human epidermoid carcinoma cell line A431
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
15mM sodium azide
Storage conditions
4°C, do not freeze
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody reacts with cytokeratin peptides 4, 5, 6, 8, 10, 13, 18. Cytokeratins are members of intermediate filaments subfamily intracellular proteins represented in epithelial tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 58 kDa cytokeratin; Cell proliferation-inducing gene 46 protein; CK-10; CK-13; CK-18; CK-4; CK-5; CK-8; cytokeratin 10; cytokeratin 13; cytokeratin 18; cytokeratin 4; cytokeratin 8; Cytokeratin-10; Cytokeratin-13; Cytokeratin-18; Cytokeratin-4; Cytokeratin-5; Cytokeratin-8; epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types; K10; K13; K18; K4; K5; K8; keratin 10, type I; keratin 13, type I; keratin 18, type I; keratin 4, type II; keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types); keratin 5, type II; keratin 8, type II; keratin K5; keratin type II; Keratin, type I cytoskeletal 10; Keratin, type I cytoskeletal 13; Keratin, type I cytoskeletal 18; Keratin, type II cytoskeletal 4; Keratin, type II cytoskeletal 5; Keratin, type II cytoskeletal 8; Keratin-10; Keratin-13; Keratin-18; Keratin-4; Keratin-5; Keratin-8; KRT5; ORF; PIG46; Type-II keratin Kb4; Type-II keratin Kb5; Type-II keratin Kb8; unnamed protein product
Gene Aliases: BCIE; BIE; CARD2; CK-18; CK-4; CK-8; CK10; CK13; CK4; CK5; CK8; CYK18; CYK4; CYK8; DDD; DDD1; EBS1; EBS2; EBS2A; EBS2B; EBS2C; EBS2D; EBS2E; EBS2F; EHK; EHK2; EHK2A; EHK2B; IHL; K10; K13; K18; K2C8; K4; K5; K8; KO; KPP; KRT10; KRT13; KRT18; KRT4; KRT5; KRT5A; KRT8; PIG46; WSN1; WSN2
UniProt ID: (Human) P13645, (Human) P13646, (Human) P05783, (Human) P19013, (Human) P13647, (Human) P05787
Entrez Gene ID: (Human) 3858, (Human) 3860, (Human) 3875, (Human) 3851, (Human) 3852, (Human) 3856
morphogenesis of an epithelium
cytoskeleton organization
epithelial cell differentiation
regulation of translation in response to stress
intermediate filament organization
keratinization
negative regulation of epithelial cell proliferation
tumor necrosis factor-mediated signaling pathway
response to other organism
cell differentiation involved in embryonic placenta development
extrinsic apoptotic signaling pathway
hepatocyte apoptotic process
peptide cross-linking
keratinocyte differentiation
positive regulation of epidermis development
protein heterotetramerization
epidermis development
response to mechanical stimulus
regulation of cell migration
regulation of protein localization
intermediate filament polymerization
anatomical structure morphogenesis
Golgi to plasma membrane protein transport
negative regulation of apoptotic process
intermediate filament cytoskeleton organization
cell-cell adhesion
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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