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Invitrogen
CD79a Monoclonal Antibody (HM57)
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FIGURE: 1 / 5
CD79a Antibody (MA5-44009) in IHC (P)
Immunohistochemical analysis of CD79a was performed using formalin-fixed paraffin-embedded human tonsil tissue sections. To expose the target protein, heat-induced epitope retrieval was performed on de-paraffinized sections using eBioscience™ IHC Antigen Retrieval Solution - High pH (10X) (Product # 00-4956-58) diluted to 1X solution in water in a decloaking chamber at 110 degree Celsius for 15 minutes. Fol... View More
Product Details
MA5-44009
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Bovine,
Chicken,
Horse,
Guinea pig,
Human,
Marsupial,
Mouse,
Pig,
Rabbit,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
HM57
Immunogen
Synthetic peptide corresponding to amino acids 202-216 of human CD79a
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
15mM sodium azide
Storage conditions
4°C, do not freeze
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody The antibody HM57 interacts with intracellular domain of CD79a (Ig alpha), a 40-45 kDa subunit of B cell antigen-specific receptor (BCR) and its early developmental forms.
Target Information
CD79a is a disulphide-linked heterodimer that includes B29 (CD79b) polypeptide. CD79a is a B lymphocyte antigen receptor with an antigen-specific surface component Ig (immunoglobulin) that associates with Ig-alpha and Ig-beta, necessary elements for the expression and function of the B-cell antigen receptor. CD79a first appears at pre-B cell stage and persists until the plasma cell stage where it is found as an intracellular component. CD79a is found in the majority of acute leukemias of precursor B cell type, in B cell lines, B cell lymphomas, and in some myelomas. It is not present in myeloid or T cell lines. Diseases associated with CD79a include Agammaglobulinemia 3 and Agammaglobulinemia, Non-Bruton type.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: B-cell antigen receptor complex-associated protein alpha chain; B-cell antigen receptor complex-associated protein alpha chain-like; CD79; CD79-alpha protein; CD79a; CD79A antigen (immunoglobulin-associated alpha); CD79a molecule, immunoglobulin-associated alpha; extracellular domain; Ig alpha; Ig-alpha; immunoglobulin-associated alpha; MB-1 membrane glycoprotein; membrane-bound immunoglobulin associated protein; Membrane-bound immunoglobulin-associated protein; signal transduction via sig in B lymphocytes; putative; similar to Homo sapiens CD79A antigen (immunoglobulin-associated alpha) encoded by GenBank Accession Number U05259; Surface IgM-associated protein; unnamed protein product
Gene Aliases: CD79A; Ig-alpha; IGA; IGAlpha; Ly-54; Ly54; MB-1; MB1
UniProt ID: (Bovine) P40293, (Human) P11912, (Mouse) P11911
Entrez Gene ID: (Bovine) 281674, (Human) 973, (Pig) 100190992, (Horse) 100052219, (Mouse) 12518, (Guinea pig) 100724815, (Rat) 100913063
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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