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Invitrogen
FGF13 Monoclonal Antibody (N235/22), FITC
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FIGURE: 1 / 3
FGF13 Antibody (MA5-45652) in ICC/IF
Immunocytochemistry/Immunofluorescence analysis using human neuroblastoma cells. Fixation involved 4% Formaldehyde for 15 min at RT. Samples were incubated with FGFA/FHFA (pan) monoclonal antibody (Product # MA5-45652) at 1:100 for 60 min at RT, followed by Goat Anti-Mouse ATTO 488 at 1:100 for 60 min at RT. Counterstain used was Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1,000; 1:5,000 for 60 min RT, 5 min RT. Localization: Cell Projection, Nucleus, Cytoplasm. Magnification: 60X. (A) DAPI (blue) nuclear stain. (B) ... View More
Product Details
MA5-45652
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
N235/22
Immunogen
Synthetic peptide amino acids 2-18 (AAAIASSLIRQKRQARE) of human FHF2A.
Conjugate
Excitation/Emission Max
498/517 nm
View spectra
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein G
Storage buffer
9.09mM sodium bicarbonate/PBS, pH 7.4, with 640.91mM DMSO, 136.36mM ethanolamine
Contains
no preservative
Storage conditions
4°C, store in dark
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
100% identical to rat, 94% identical to mouse. >80% identity with FGF12A/FHF1A, FGF14A/FHF4A and FGF11A/FHF3A.
1 µg/mL of MA5-45652 was sufficient for detection of FGFA/FHFA (pan) in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.|Detects approximately 30kDa. Does not cross-react with FGF13B/FHF2B. Cross reacts with FGF12A/FHF1A and FGF14A/FHF4A.
This antibody was formerly sold as clone S235-22.
Target Information
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This gene is located in a region on chromosome X, which is associated with Borjeson-Forssman-Lehmann syndrome (BFLS), making it a possible candidate gene for familial cases of the BFLS, and for other syndromal and nonspecific forms of X-linked mental retardation mapping to this region. Alternative splicing of this gene at the 5' end results in several transcript variants encoding different isoforms with different N-termini.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AFGF; ECGF; ECGFA; ECGFB; FGF; FGF 1; FGF alpha; FGF-13; FGF13A; FGFA; FHF-2; FHF2-1A; FHF2-1B; Fibroblast growth factor; Fibroblast growth factor 13; Fibroblast growth factor homologous factor 2; GLIO703; HBGF 1; HBGF1; hFHF-2(1X+1W+1V); hFHF-2(1Z+1Y); unnamed protein product
Gene Aliases: DEE90; FGF-13; FGF13; FGF2; FHF-2; FHF2; LINC00889; XLID110
UniProt ID: (Human) Q92913, (Rat) Q9ERW3, (Mouse) P70377
Entrez Gene ID: (Human) 2258, (Rat) 84488, (Mouse) 14168
MAPK cascade
neuron migration
sodium ion transport
negative regulation of microtubule depolymerization
signal transduction
cell-cell signaling
nervous system development
learning or memory
learning
memory
hippocampus development
cerebral cortex cell migration
neurogenesis
establishment of neuroblast polarity
microtubule polymerization
negative regulation of collateral sprouting
branching morphogenesis of a nerve
protein localization to plasma membrane
regulation of cardiac muscle cell action potential involved in regulation of contraction
inhibitory synapse assembly
positive regulation of voltage-gated sodium channel activity
apoptotic process
cell proliferation
positive regulation of protein kinase activity
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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