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Invitrogen
RAB1A Monoclonal Antibody (4G10), PerCP
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Product Details
MA5-45968
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
4G10
Immunogen
Full length recombinant RAB1A protein
Conjugate
Excitation/Emission Max
482/675 nm
View spectra
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein G
Storage buffer
95.64mM phosphate/2.48mM MES, pH 7.4, with 0.5M EDTA
Contains
no preservative
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
A 1:1,000 dilution of MA5-45968 was sufficient for detection of RAB1A in 10 µg (A549, MEF); 20 µg (Mouse Brain) lysates by ECL immunoblot analysis.
Detects approximately 23 kDa. Cross-reacts with RAB1B and RAB1C.
Target Information
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a member of the L18AE family of ribosomal proteins that is a component of the 60S subunit. The encoded protein may play a role in viral replication by interacting with the hepatitis C virus internal ribosome entry site (IRES). This gene is co-transcribed with the U68 snoRNA, located within the third intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed throughout the genome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DKFZP564B163; GTP binding protein Rab1a; Rab GTPase YPT1 homolog; RAB1, member RAS oncogene family; RAB1A; Ras-related protein Rab-1A; ras-related YPT1 protein; unnamed protein product; YPT1-related protein
Gene Aliases: Gtbp; mKIAA3012; Rab-1; RAB1; RAB1A; YPT1
UniProt ID: (Human) P62820, (Mouse) P62821
Entrez Gene ID: (Human) 5861, (Mouse) 19324
autophagosome assembly
intracellular protein transport
ER to Golgi vesicle-mediated transport
endocytosis
autophagy
Golgi organization
protein transport
vesicle-mediated transport
cell migration
virion assembly
growth hormone secretion
melanosome transport
positive regulation of interleukin-8 production
substrate adhesion-dependent cell spreading
defense response to bacterium
vesicle transport along microtubule
cilium morphogenesis
cargo loading into COPII-coated vesicle
establishment of endothelial intestinal barrier
positive regulation of glycoprotein metabolic process
transport
small GTPase mediated signal transduction
Rab protein signal transduction
interleukin-8 secretion
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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