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Invitrogen
CEACAM6 Recombinant Rabbit Monoclonal Antibody (408), APC
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FIGURE: 1 / 1
CEACAM6 Antibody (MA5-46694) in Flow
Flow cytometry analysis of CD66c (CEACAM6) in human whole blood granulocytes using CEACAM6, APC Recombinant Monoclonal (Product # MA5-46694). The histogram were derived from gated events with the forward and side light-scatter characteristics of viable granulocytes.
Product Details
MA5-46694
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
408
Immunogen
Recombinant protein ecoding Human CEACAM6 (Met1-Gly320).
Conjugate
Excitation/Emission Max
651/660 nm
View spectra
Form
Liquid
Concentration
100 µg/mL
Purification
Protein A
Storage buffer
PBS with 0.5% BSA
Contains
0.03% ProClin 300
Storage conditions
4°C, store in dark, DO NOT FREEZE!
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Preparation: This antibody was obtained from a rabbit immunized with purified, recombinant Human CD66c (CEACAM6) (Met1-Gly320) and conjugated with APC under optimum conditions, the unreacted APC was removed.
Storage: This antibody can be stored at 2C-8C for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
Target Information
CEA Cell Adhesion Molecule 6 (CEACAM6) belongs to the carcinoembryonic antigen (CEA) family whose members are glycosyl phosphatidyl inositol (GPI) anchored cell surface glycoproteins. Members of this family play a role in cell adhesion and are widely used as tumor markers in serum immunoassay determinations of carcinoma. CEACAM6 affects the sensitivity of tumor cells to adenovirus infection. The acts as a receptor for adherent-invasive E. coli adhesion to the surface of ileal epithelial cells in patients with Crohn's disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BGP; BGP-1; carcinoembryonic antigen related cell adhesion molecule 6; Carcinoembryonic antigen-related cell adhesion molecule 6; carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen); CD66a; CD66c; CD66d; CD66e; CEA; CEA cell adhesion molecule 6; CEACAM-1; CEACAM-3; CEACAM-5; CEACAM-6; Cell adhesion molecule CEACAM6; CGM1; Cluster of Differentiation 66c; Non-specific crossreacting antigen; nonspecific crossreacting antigen precursor; Normal cross-reacting antigen; ORF1; ORF2; pan CEACAM; unnamed protein product
Gene Aliases: CD66c; CEACAM6; CEAL; NCA; NCA-50/90
UniProt ID: (Human) P40199
Entrez Gene ID: (Human) 4680
apoptotic process
cell adhesion
homophilic cell adhesion via plasma membrane adhesion molecules
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
positive regulation of cell proliferation
positive regulation of cell migration
positive regulation of heterotypic cell-cell adhesion
positive regulation of endothelial cell-matrix adhesion via fibronectin
negative regulation of anoikis
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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