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TNFR2 Recombinant Rabbit Monoclonal Antibody (112), PE
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FIGURE: 1 / 1
TNFR2 Antibody (MA5-52373) in Flow
Flow cytometry analysis of mouse TNFRSF1B(CD120b) expression on L929 cells. Samples were incubated with TNFR2 monoclonal antibody (Product # MA5-52373). The histogram were derived from gated events with the forward and side light-scatter characteristics of intact cells.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-52373
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
112
Immunogen
Recombinant Mouse TNFR2/CD120b/TNFRSF1B protein (1-258).
Conjugate
PE
PE
PE
Excitation/Emission Max
565/576 nm
View spectra
Form
Liquid
Concentration
100 µg/mL
Purification
Protein A
Storage buffer
PBS with 0.5% BSA
Contains
0.09% sodium azide
Storage conditions
4°C, store in dark, DO NOT FREEZE!
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
TNFR2 (tumor necrosis factor receptor superfamily member 1B) is a receptor with high affinity for TNFSF2/TNF-alpha. It has a much lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. TNFR2 mediates most of the metabolic effects of TNF-alpha.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: p75 TNFR; p80 TNF-alpha receptor; sCD120b; soluble CD120b; soluble TNFR2; sTNF R2; sTNFR 2; sTNFR2; TNF receptor beta chain; TNF-RII; TNFR; TNFR II; TNFR-II; Tumor necrosis factor receptor; tumor necrosis factor receptor 2; tumor necrosis factor receptor type II; unnamed protein product
Gene Aliases: CD120b; p75; TNF-alphaR2; TNF-R-II; TNF-R2; TNF-R75; TNFalpha-R2; TNFBR; Tnfr-1; Tnfr2; TNFR80; TNFRII
UniProt ID: (Mouse) P25119
Entrez Gene ID: (Mouse) 21938
regulation of cytokine production involved in immune response
regulation of T cell cytokine production
aortic valve development
pulmonary valve development
negative regulation of extracellular matrix constituent secretion
inflammatory response
immune response
cell surface receptor signaling pathway
intrinsic apoptotic signaling pathway in response to DNA damage
negative regulation of cardiac muscle hypertrophy
regulation of myelination
positive regulation of myelination
tumor necrosis factor-mediated signaling pathway
regulation of T cell proliferation
positive regulation of oligodendrocyte differentiation
negative regulation of inflammatory response
RNA destabilization
positive regulation of membrane protein ectodomain proteolysis
cellular response to lipopolysaccharide
extrinsic apoptotic signaling pathway
regulation of neuroinflammatory response
negative regulation of neuroinflammatory response
glial cell-neuron signaling
positive regulation of apoptotic process involved in morphogenesis
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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