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Invitrogen
Influenza A NP Recombinant Rabbit Monoclonal Antibody (014)
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Product Details
MA5-60359
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Virus
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
014
Immunogen
Recombinant Influenza A H3N2 (A/Hong Kong/1/1968) Nucleoprotein/NP protein (Met1-Asn498).
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Widely recognize Influenza A Nucleoprotein. Has cross-reactivity in WB and ELISA with: H3N2 (A/Darwin/9/2021)/(A/Darwin/6/2021) NP Protein. Has cross-reactivity in ELISA with: H1N1 (A/Brevig Mission/1/1918) NP; H1N1 (A/Brisbane/02/2018) NP; H1N1 (A/California/07/2009) NP; H1N1 (A/Guangdong-Maonan/SWL1536/2019) NP; H1N1 (A/Hawaii/70/2019) NP; H1N1 (A/Michigan/45/2015 NP; H1N1 (A/Puerto Rico/8/34/Mount Sinai) NP (I116M); H1N1 (A/Victoria/2454/2019) NP; H1N1 (A/Victoria/2570/2019)/(A/Wisconsin/588/2019) NP; H2N2 (A/Ann Arbor/6/1960) NP; H3N2 (A/Aichi/2/1968) NP; H3N2 (A/Cambodia/e0826360/2020 (H3N2)-like NP; H3N2 (A/Hong Kong/1/1968) NP; H3N2 (A/Hong Kong/2671/2019) NP; H3N2 (A/Hong Kong/45/2019) NP; H3N2 (A/Hong Kong/4801/2014) NP; H3N2 (A/Kansas/14/2017) NP; H3N2 (A/Switzerland/9715293/2013) NP; H5N1 (A/Texas/37/2024) NP Protein; H7N9 (A/Anhui/1-BALF_RG6/2013) NP; H7N9 (A/Shanghai/2/2013) NP; Influenza B (B/Brisbane/60/2008) NP; Influenza B (B/Colorado/06/2017) NP; Influenza B (B/Phuket/3073/2013) NP; Influenza B (B/Washington/02/2019) NP; No cross-reactivity in WB and ELISA with: Influenza B (B/Austria/1359417/2021) NP Protein; Influenza B (B/Phuket/3073/2013) NP Protein; No cross-reactivity in ELISA with: Influenza B (B/Florida/4/2006) NP; SARS-CoV-2 Nucleocapsid Protein; HCoV-229E Nucleocapsid Protein HCoV-NL63 Nucleocapsid Protein; HCoV-HKU1 Nucleocapsid Protein; HCoV-OC43 Nucleocapsid Protein; No cross-reactivity in WB with: H1N1 (A/Brevig Mission/1/1918) NP Protein; H5N1 (A/Texas/37/2024) NP Protein
Target Information
The nucleoprotein (NP) of Influenza A virus encapsidates the negative strand of the viral RNA and is essential for replicative transcription. It may also be involved in other essential functions throughout the virus life cycle. As well as binding ssRNA, NP is able to self associate to form large oligomeric complexes. NP is able to interact with a variety of other macromolecules of both viral and cellular origins. It binds the PB1 and PB2 subunits of the polymerase and the matrix protein M1. "NP has also been shown to interact with at least four cellular polypeptide families: nuclear import receptors of the importin class, filamentous (F) actin, the nuclear export receptor CRM1 and a DEAD box helicase BAT1/UAP56" (Portela et al 2002).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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