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Invitrogen
IL2RG Monoclonal Antibody (TUGh4), APC
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FIGURE: 1 / 3
IL2RG Antibody (MA562192) in Flow
Flow cytometry (multicolor surface staining) of IL2RG in human lymphocytes. Samples were stained with IL2RG monoclonal antibody (Product # MA562192) using a dilution of 10 µL reagent/100 µL of peripheral whole blood with anti-human CD45 (MEM-28) Pacific Blue™ antibody at 4 µL reagent/100 µL of peripheral whole blood.
Product Details
MA562192
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Dog,
Human
Host/Isotype
Rat
/ IgG2b, kappa
Class
Monoclonal
Type
Antibody
Clone
TUGh4
Immunogen
Human CD132-transfected cell line.
Conjugate
Excitation/Emission Max
651/660 nm
View spectra
Form
Liquid
Concentration
0.065 mg/mL
Purification
Size-exclusion chromatography
Storage buffer
PBS, pH 7.4, with 0.2% BSA
Contains
15mM sodium azide
Storage conditions
4°C, store in dark, DO NOT FREEZE!
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
IL2RG is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in this gene cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD132; CD132 antigen; common cytokine receptor gamma chain; Cytokine receptor common subunit gamma; gammaC; IL-2 receptor subunit gamma; IL-2R subunit gamma; IL-2RG; IL2R gamma; interleukin 2 receptor gamma chain; interleukin 2 receptor, gamma; interleukin 2 receptor, gamma (severe combined immunodeficiency); Interleukin-2 receptor subunit gamma; nonfunctional common cytokine receptor gamma chain; p64; unnamed protein product
Gene Aliases: CD132; CIDX; IL-2RG; IL2RG; IMD4; P64; SCIDX; SCIDX1
UniProt ID: (Human) P31785, (Dog) P40321
Entrez Gene ID: (Human) 3561, (Dog) 403851
mature B cell differentiation
CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation
immune system process
positive regulation of immunoglobulin production
immune response
signal transduction
gene expression
regulation of gene expression
positive regulation of gene expression
cytokine-mediated signaling pathway
cellular homeostasis
lymphocyte differentiation
B cell differentiation
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation
T cell differentiation in thymus
positive regulation of T cell differentiation in thymus
interleukin-15-mediated signaling pathway
interleukin-4-mediated signaling pathway
interleukin-2-mediated signaling pathway
interleukin-7-mediated signaling pathway
interleukin-9-mediated signaling pathway
positive regulation of B cell differentiation
positive regulation of phagocytosis
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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