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Invitrogen
TRIM Monoclonal Antibody (TRIM-04), Alexa Fluor™ 647
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FIGURE: 1 / 3
TRIM Antibody (MA574241) in Flow
Flow cytometry analysis of TRIM in human CD3 positive TRIM positive T cells (red-filled); CD3 negative TRIM negative lymphocytes (black-dashed). Samples were incubated with monoclonal TRIM (Product # MA574241) at a dilution of 1.67 μg/mL, followed by Alexa Fluor 647.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA574241
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
TRIM-04
Immunogen
Recombinant intracellular domain (aa 29-186) of human TRIM.
Conjugate
Alexa Fluor™ 647
Alexa Fluor™ 647
Alexa Fluor™ 647
Excitation/Emission Max
650/671 nm
View spectra
Form
Liquid
Concentration
0.1 mg/mL
Amount
100 µg
Purification
Size-exclusion chromatography
Storage buffer
PBS, pH 7.4, with 0.2% BSA
Contains
15mM sodium azide
Storage conditions
4°C, store in dark, DO NOT FREEZE!
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
TRIM (T cell receptor-interacting molecule), also known as TRAT1 (T cell receptor associated transmembrane adaptor 1) is a 30 kDa protein expressed by T cells as a cystein-linked homodimer. It associates with TCR-CD3-zeta-chain complex and becomes phosphorylated by Src-family kinases. TRIM is potentially involved in negative regulation of TCR-mediated signaling, but its role remains unclear.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: T cell receptor interacting molecule; unnamed protein product
Gene Aliases: HSPC062; pp29/30; TCRIM; TRIM
UniProt ID: (Human) Q6PIZ9
Entrez Gene ID: (Human) 50852
Disclaimer
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