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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 427 and 714 of Human MAD1|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 1% BSA, 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-28185 targets MAD1 in IF, IHC (P), and WB applications and shows reactivity with Human samples.
The PA5-28185 immunogen is recombinant fragment corresponding to a region within amino acids 427 and 714 of Human MAD1.
MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Three transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
homolog-like 1; MAD1 mitotic arrest deficient-like 1; MAD1-like protein 1; mitotic arrest deficient 1-like protein 1; mitotic checkpoint MAD1 protein homolog; mitotic spindle assembly checkpoint protein MAD1; mitotic-arrest deficient 1; mitotic-arrest deficient 1, yeast, homolog-like 1; PIG9; tax-binding protein 181; TP53I9; tumor protein p53 inducible pr; tumor protein p53 inducible protein 9; TXBP181; yeast
MAD1; MAD1L1; PIG9; TP53I9; TXBP181