This Antibody was verified by KnockDown to ensure that the antibody binds to the antigen stated. View Details
PA5-28991 targets Mad 1 in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-28991 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 367 of Human Mad 1.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Three transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: homolog-like 1; HsMAD1; MAD1 mitotic arrest deficient-like 1; MAD1-like protein 1; mitotic arrest deficient 1-like 1; Mitotic arrest deficient 1-like protein 1; Mitotic checkpoint MAD1 protein homolog; Mitotic spindle assembly checkpoint protein MAD1; mitotic-arrest deficient 1; mitotic-arrest deficient 1, yeast, homolog-like 1; PIG9; Tax-binding protein 181; TP53I9; tumor protein p53 inducible pr; tumor protein p53 inducible protein 9; TXBP181; yeast
Gene Aliases: AI173502; AW550425; MAD1; MAD1L1; PIG9; TP53I9; TXBP181