Immunogen sequence: RGLEKARQQL QEELRQVSGQ LLEERKKRET HEALARRLQK RVLLLTKERD GMRAILGSYD SELTPAEYSP QLTRRMREAE DMVQKVHSHS AEMEAQLSQA LEELGGQKQR ADMLEMELKM LKSQSSSAEQ SFLFSREEAD TLRLKVEELE GERSRLEEEK RMLEAQLERR ALQGDYDQSR TKVLHMSLNP TSVARQRLRE DHSQLQAECE RLRGLLRAME RGGTVPADLE AAAASLPSSK EVAELKKQVE SAELKNQRLK EVFQTKIQEF RKACYTLTGY QIDITTENQY RLTSLYAEHP GDCLIFKATS PSGSKMQLLE TEFSHTVGEL IEVHLRRQDS I; Positive Samples: HeLa, HepG2, MCF7; Cellular Location: Chromosome, Cytoplasm, Nucleus, centromere, centrosome, cytoskeleton, kinetochore, microtubule organizing center, spindle
MAX dimerization protein belongs to a subfamily of MAX-interacting proteins. This protein competes with MYC for binding to MAX to form a sequence-specific DNA-binding complex, acts as a transcriptional repressor (while MYC appears to function as an activator) and is a candidate tumor suppressor.
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Protein Aliases: HsMAD1; MAD1 mitotic arrest deficient-like 1; MAD1-like protein 1; mitotic arrest deficient 1-like 1; Mitotic arrest deficient 1-like protein 1; Mitotic checkpoint MAD1 protein homolog; Mitotic spindle assembly checkpoint protein MAD1; mitotic-arrest deficient 1, yeast, homolog-like 1; Tax-binding protein 181; tumor protein p53 inducible protein 9
Gene Aliases: AI173502; AW550425; MAD1; MAD1L1; PIG9; TP53I9; TXBP181