PA1-30689 detects MADD from human, mouse samples.
PA1-30689 has been successfully used in Western blot applications.
The PA1-30689 immunogen is: Synthetic peptide - amino acids 1570 to 1588 of human MADD. This sequence is identical to that of DENN and differs by one amino acid with rat GDP/GTP exchange protein RAb3-GEP.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
Tumor necrosis factor receptor 1 (TNFR1) contains a death receptor domain that mediates interactions involved in downstream signaling of TNF. A novel protein, MADD (mitogen activated protein (MAP)-kinase activating death domain protein) has recently been
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Protein Aliases: DENN; Differentially Expressed in Neoplasmic vs. Normal Cells; Differentially expressed in normal and neoplastic cells; Insulinoma glucagonoma clone 20; insulinoma-glucagonoma protein 20; MADD; MAP kinase-activating death domain protein; MAP-Kinase Activating Death Domain; Rab3 GDP/GTP exchange factor; Rab3 GDP/GTP exchange protein; Rab3 GEP
Gene Aliases: 9630059K23Rik; DENN; IG20; KIAA0358; MADD; RAB3GEP