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Proteintech
MAFB Polyclonal Antibody, CoraLite® Plus 488
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FIGURE: 1 / 1
MAFB Antibody (CL488-20189) in Flow
1x10^6 RAW 264.7 cells were intracellularly stained with 0.4 µg Coralite® Plus 488 MAFB Polyclonal Antibody (CL488-20189) (red), or 0.4 µg CoraLite® Plus 488-conjugated Rabbit IgG control Rabbit PolyAb (CL488-30000) (blue). Cells were fixed and permeabilized with Transcription Factor Staining Buffer Kit (PF00011).
Product Details
CL488-20189
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
MAFB fusion protein Ag14102
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 0.5% BSA, 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: QASPPPSSA ASPAQQLPTS HPGPGPHATA SATAAGGNGS VEDRFSDDQL VSMSVRELNR HLRGFTKDEV IRLKQKRRTL KNRGYAQSCR YKRVQQKHHL ENEKTQLIQQ VEQLKQEVSR LARERDAYKV KCEKLANSGF REAGSTSDSP SSPEFFL
Target Information
The protein encoded by this gene is a basic leucine zipper transcription factor that plays an important role in the regulation of lineage-specific hematopoiesis. The encoded nuclear protein represses ETS1-mediated transcription of erythroid-specific genes in myeloid cells. This gene contains no introns.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: bZIP transcription factor; Kreisler; Kreisler (maf-related) leucine zipper protein; Kreisler maf-related leucine zipper homolog; Kreisler maf-related leucine zipper homolog (b-maf); Maf-B; MAFB/Kreisler basic region/leucine zipper transcription factor; MGC43127; Segmentation protein Kr; Transcription factor Maf-1; Transcription factor MafB; unnamed protein product; v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B; v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B; V-maf musculoaponeurotic fibrosarcoma oncogene homolog B
Gene Aliases: b-maf; DURS3; kr; Kreisler; KRML; Krml1; Maf1; MAFB; MCTO
UniProt ID: (Human) Q9Y5Q3, (Rat) P54842, (Mouse) P54841
Entrez Gene ID: (Human) 9935, (Rat) 54264, (Mouse) 16658
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
identical protein binding
sequence-specific DNA binding
macromolecular complex binding
sequence-specific double-stranded DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor binding
basic leucine zipper transcription factor
negative regulation of transcription from RNA polymerase II promoter
in utero embryonic development
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
segment specification
sensory organ development
response to nutrient
respiratory gaseous exchange
gene expression
protein processing
rhombomere 5 development
rhombomere 6 development
abducens nerve formation
keratinocyte differentiation
T cell differentiation in thymus
brain segmentation
inner ear morphogenesis
fat cell differentiation
regulation of myeloid cell differentiation
negative regulation of erythrocyte differentiation
negative regulation of osteoclast differentiation
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
thymus development
integrated stress response signaling
cornified envelope assembly
transcription, DNA-templated
transcription from RNA polymerase II promoter
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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