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|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 1 and 162 of Human MAFG|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-30086 targets MAFG in IF, IHC (P), and WB applications and shows reactivity with Human, Mouse and Rat samples.
The PA5-30086 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 162 of Human MAFG.
Globin gene expression is regulated through nuclear factor erythroid-2 (NFE2) elements located in enhancer-like locus control regions positioned many kb upstream of alpha- and beta-gene clusters (summarized by Blank et al., 1997 [PubMed 9166829]). NFE2 DNA-binding activity consists of a heterodimer containing a ubiquitous small Maf protein (MafF, MIM 604877; MafG; or MafK, MIM 600197) and the tissue-restricted protein p45 NFE2 (MIM 601490). Both subunits are members of the activator protein-1-like superfamily of basic leucine zipper (bZIP) proteins (see MIM 165160).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
avian musculoaponeurotic fibrosarcoma virus (v-maf) AS42 oncogene, protein G; basic leucine zipper transcription factor MafG; transcription factor MafG; v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G; v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G; V-maf musculoaponeurotic fibrosarcoma oncogene homolog G
AA545192; C630022N07Rik; hMAF; MAFG