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Invitrogen
MAGEA2 Polyclonal Antibody
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FIGURE: 1 / 1
MAGEA2 Antibody (PA5-97947) in WB
Western Blot analysis of MAGEA2 using a MAGEA2 Polyclonal antibody (Product # PA5-97947) at a concentration of 4.4 µg/mL. Positive WB detected in: K562 whole cell lysate, Raji whole cell lysate. A secondary Goat polyclonal antibody to rabbit IgG was applied at a 1:50,000 dilution. Observed band size: 36 kDa.
Product Details
PA5-97947
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human Melanoma-associated antigen 2 protein (1-104AA)
Conjugate
Form
Liquid
Concentration
4.39 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.03% ProClin 300
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
MAGEA2 is a member of the MAGEA gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 80% sequence identity between each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are expressed at a high level in a number of tumors of various histologic types, and are silent in normal tissues with the exception of testis and placenta. The MAGEA genes are clustered on chromosome Xq28. They may be implicated in some hereditary disorders, such as dyskeratosis congenita. This gene has two identical copies at different loci.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cancer/testis antigen 1.2; cancer/testis antigen family 1, member 2; CT1.2; MAGE-2 antigen; melanoma antigen 2; melanoma antigen family A, 2; melanoma antigen family A2; Melanoma-associated antigen 2; MGC131923
Gene Aliases: CT1.2; MAGE2; MAGEA2; MAGEA2A; MAGEA2B
UniProt ID: (Human) P43356
Entrez Gene ID: (Human) 4101
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
negative regulation of protein sumoylation
cellular protein catabolic process
positive regulation of ubiquitin-protein transferase activity
signal transduction by p53 class mediator
cellular senescence
negative regulation of protein acetylation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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