This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
Immunogen sequence: LKVAHATAAE KEECPSSSPV LGDTPTSSPA AGIPQKPQGA PPTTTAAAAV SCTESDEGAK CQGEENASFS QATTSTESSV KDPVAWEAGM LMHFILRKYK MREPIMKADM LKVVDEKYKD HFTEILNGAS R
Highest antigen sequence identity to the following orthologs: Mouse - 39%, Rat - 38%.
This gene is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. This gene is localized in the DSS (dosage-sensitive sex reversal) critical region, and expressed in testis and in a significant fraction of tumors of various histological types. This gene and other MAGEB members are clustered on chromosome Xp22-p21. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene, however, the full length nature of some variants has not been defined.
Protein Aliases: Cancer/testis antigen 3.1; cancer/testis antigen family 3, member 1; CT3.1; DAM10; DSS-AHC critical interval MAGE superfamily 10; DSS/AHC critical interval MAGE superfamily 10; MAGE-B1 antigen; MAGE-XP antigen; melanoma antigen family B, 1; melanoma antigen family B1; Melanoma-associated antigen B1; MGC9322
Gene Aliases: CT3.1; DAM10; MAGE-Xp; MAGEB1; MAGEL1; MAGEXP
UniProt ID: (Human) P43366
Entrez Gene ID: (Human) 4112
Molecular Function: scaffold/adaptor protein