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Product Details
17494-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
MAGEB18 Fusion Protein Ag11624 (1-343 aa encoded by BC029525)
Conjugate
Form
Liquid
Concentration
0.17 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MPRGQKSKL RAREKRHQAR CENQDLGATQ ATVAEGESPS SAYLLFGDRP QNLPAAETPS IPEALQGAPS TTNAIAPVSC SSNEGASSQD EKSLGSSREA EGWKEDPLNK KVVSLVHFLL QKYETKEPIT KGDMIKFVIR KDKCHFNEIL KRASEHMELA LGVDLKEVDP IRHYYAFFSK LDLTYDETTS DEEKIPKTGL LMIALGVIFL NGNRAPEEAV WEIMNMMGVY ADRKHFLYGD PRKVMTKDLV QLKYLEYQQV PNSDPPRYEF LWGPRAHAET SKMKVLEFVA KIHDTVPSAF PSCYEEALRD EEQRTQARAA ARAHTAAMAN ARSRTTSSSF SHAK (1-343 aa encoded by BC029525)
Target Information
The melanoma-associated antigen (MAGE) family consists of a number of antigens recognized by cytotoxic T lymphocytes. The MAGE genes were initially isolated from different kinds of tumors and, based on their virtually exclusive tumor-specific expression in adult tissues, they have been used as targets for cancer immunotherapy. MAGE genes encode for tumor-rejection antigens that are expressed in tumors of different histologic types and in normal testis and placenta. MAGE-B18 (melanoma-associated antigen B18) is a 343 amino acid protein that contains one MAGE domain and may be involved in tumorigenesis. The gene encoding MAGE-B18 maps to human chromosome X, which contains nearly 153 million base pairs and houses over 1,000 genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MAGBI; MAGE-B18 antigen; melanoma antigen family B, 18; melanoma antigen family B18; Melanoma-associated antigen B18
Gene Aliases: MAGEB18
UniProt ID: (Human) Q96M61
Entrez Gene ID: (Human) 286514
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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