This gene is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. This gene is expressed in testis, and in a significant fraction of tumors of various histological types. The MAGEB genes are clustered on chromosome Xp22-p21.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cancer/testis antigen 3.4; cancer/testis antigen family 3, member 4; CT3.4; MAGE-B6 antigen; melanoma antigen family B, 6; melanoma antigen family B6; Melanoma-associated antigen B6
Gene Aliases: CT3.4; MAGE-B6; MAGEB6; MAGEB6A
UniProt ID: (Human) Q8N7X4
Entrez Gene ID: (Human) 158809
Molecular Function: cell adhesion molecule