Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
MAGED1 Polyclonal Antibody
Advanced Verification
This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
Product Details
PA5-65365
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human MAGED1. Recombinant protein control fragment (Product #RP-104776).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2665274
Product Specific Information
Immunogen sequence: ARPKSAFKVQN ATTKGPNGVY DFSQAHNAKD VPNTQPKAAF KSQNATPKGP NAAYDFSQAA TTGELAANKS EMAFKAQNAT TKVGPNATYN FSQSLNANDL ANSRPKTPFK AWNDTTKAPT ADTQTQNVNQ AKMATSQADI ETDPGISEP
Highest antigen sequence identity to the following orthologs - mouse 67%, rat 68%.
Target Information
This gene is a member of the melanoma antigen gene (MAGE) family. Most of the genes of this family encode tumor specific antigens that are not expressed in normal adult tissues except testis. Although the protein encoded by this gene shares strong homology with members of the MAGE family, it is expressed in almost all normal adult tissues. This gene has been demonstrated to be involved in the p75 neurotrophin receptor mediated programmed cell death pathway. Three transcript variants encoding two different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: JCL-1; MAGE tumor antigen CCF; MAGE-D1 antigen; Maged2; melanoma antigen family D, 1; melanoma antigen family D1; Melanoma-associated antigen D1; Neurotrophin receptor-interacting MAGE homolog
Gene Aliases: DLXIN-1; MAGED1; NRAGE; PP2250; PRO2292
UniProt ID: (Human) Q9Y5V3
Entrez Gene ID: (Human) 9500
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
circadian regulation of gene expression
regulation of circadian rhythm
regulation of apoptotic process
positive regulation of MAP kinase activity
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
negative regulation of epithelial cell proliferation
positive regulation of branching involved in ureteric bud morphogenesis
positive regulation of apoptotic signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support