Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Immunogen sequence: LGKLGMQPGR QHSIFGDPKK IVTEEFVRRG YLIYKPVPRS SPVEYEFFWG PRAHVESSKL KVMHFVARVR NRCSKDWPCN YDWDSDDDAE VEAILNSGAR G
Melanoma-associated antigen (MAGE) are completely silent in normal tissues, with the exception of male germ cells, and, for some of them, placenta. These antigens ought to be strictly tumor specific, expressed in tumor cells of various histological types. Because of their specific expression on tumor cells, these antigens are of particular interest for antitumor immunotherapy. Genes of the MAGE family direct the expression of tumor antigens that are recognized on a human melanoma by autologous cytolytic T lymphocytes. Though the function of MAGEH1 is not fully elucidated, it may play a role in embryonal development and tumor transformation or aspects of tumor progression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 1-Apr; Apoptosis-related protein 1; APR-1; MAGE-H1 antigen; melanoma antigen family H, 1; melanoma antigen family H1; Melanoma-associated antigen H1; Restin
Gene Aliases: APR-1; APR1; MAGEH; MAGEH1
UniProt ID: (Human) Q9H213
Entrez Gene ID: (Human) 28986
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support