MAGT1 encodes a magnesium cation transporter protein that localizes to the cell membrane. This protein also associates with N-oligosaccharyl transferase and therefore may have a role in N-glycosylation. Mutations in this gene cause mental retardation X-linked type 95 (MRX95). This gene may have multiple in-frame translation initiation sites, one of which would encode a shorter protein with an N-terminus containing a signal peptide at amino acids 1-29.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1; IAP; Implantation-associated protein; Magnesium transporter protein 1; MagT1; Oligosaccharyl transferase subunit MAGT1; oligosaccharyltransferase 3 homolog B
Gene Aliases: 2410001C15Rik; 2610529C04Rik; 2810482I07Rik; bA217H1.1; IAG2; IAP; MAGT1; MRX95; OST3B; PRO0756; PSEC0084; UNQ628/PRO1244; XMEN
Molecular Function: glycosyltransferase