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Invitrogen
MALT1 Polyclonal Antibody
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FIGURE: 1 / 3
MALT1 Antibody (PA5-79622) in WB
Western blot was performed using Anti-MALT1 Polyclonal Antibody (Product # PA5-79622) and a 92 kDa band corresponding to MALT1 along with uncharacterized bands(*) was observed in Hela, Raji, Jurkat and PC-3. Whole cell extracts (30 µg lysate) of HeLa (Lane 1), Raji (Lane 2), Jurkat (Lane 3) and PC-3 (Lane 4) were electrophoresed using Novex® NuPAGE® 4-12 % Bis-Tris gel (Product # NP0322BOX). Resolved proteins were then transferred onto a nitrocellulose membrane (Product # IB23001) by iBlot® 2 Dry Blotting System (Product # IB21001). The bl... View More
Product Details
PA5-79622
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human MALT1 (809-824aa DEIPFSFSDRLRISEK).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5mg BSA
Contains
0.05mg sodium azide, 0.05mg thimerosal
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: MCF-7 Cell, HELA Cell.
Target Information
MALT1/Paracaspase (MALT1) was independently identified as a member of the human paracaspase family and an interacting partner of B-cell lymphoma (Uren et al., 2000). MALT1 is a caspase-like protein that contains an N-terminal death domain, two Ig-like domains, and a C-terminal caspase-like domain. It binds to Bcl10 through its Ig-like domains and cooperates with Bcl10 to activate NF-kappaB.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: caspase-like protein; DKFZp434L132; MALT lymphoma-associated translocation; malt-1; MALT1 protease; MALT1; MLT1; mucosa associated lymphoid tissue lymphoma translocation gene 1; Mucosa-associated lymphoid tissue lymphoma translocation protein 1; Paracaspase; paracaspase-1; unnamed protein product
Gene Aliases: IMD12; MALT1; MLT; MLT1; PCASP1
UniProt ID: (Human) Q9UDY8
Entrez Gene ID: (Human) 10892
B-1 B cell differentiation
immune system process
positive regulation of immune effector process
positive regulation of T cell cytokine production
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
proteolysis
defense response
response to fungus
regulation of signal transduction
positive regulation of protein ubiquitination
lipopolysaccharide-mediated signaling pathway
positive regulation of interleukin-1 beta production
positive regulation of interleukin-2 production
T cell proliferation
B cell activation
regulation of apoptotic process
negative regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
innate immune response
T cell receptor signaling pathway
regulation of T cell receptor signaling pathway
positive regulation of T cell activation
nuclear export
positive regulation of multicellular organismal process
proteolysis involved in cellular protein catabolic process
cellular response to lipopolysaccharide
positive regulation of T-helper 17 cell differentiation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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