Positive Control: HeLa, HeLa nuclear extract
Predicted Reactivity: Mouse (88%), Bovine (97%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
MAML2 acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1. Potentiates activation by NOTCH3 and NOTCH4 more efficiently than MAML1 or MAML3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Mam-2; MAM-3; MAM2; MAM3; mastermind-like 2; mastermind-like 2 (Drosophila); Mastermind-like protein 2; mastermind-like transcriptional coactivator 2; MLL-MAML2
Gene Aliases: KIAA1819; MAM-3; MAM2; MAM3; MAML2; MLL-MAML2
UniProt ID: (Human) A7MD26
Entrez Gene ID: (Human) 84441
Molecular Function: transcription factor