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|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 640-665 amino acids from the C-terminal region of human MAML3|
|Purification||Ammonium sulfate precipitation, Size-exclusion - Dialysis|
|Contains||0.09% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||1:10-1:50|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Western Blot (WB)||See 1 publications below|
MAML3 acts as a transcriptional coactivator for NOTCH proteins. The protein has been shown to amplify NOTCH-induced transcription of HES1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Notch-dependent RBPJ¿ inhibits proliferation of human cytotrophoblasts and their differentiation into extravillous trophoblasts.
PA5-13678 was used in western blot to investigate the signalling pathways involved in the development of invasive trophoblasts
|Velicky P,Haider S,Otti GR,Fiala C,Pollheimer J,Knöfler M||Molecular human reproduction (20:756)||2014|
CAG repeat containing (glia-derived nexin I alpha); CAG repeat domain; expanded repeat domain, CAG/CTG 3; KIAA1816; Mam-3; MAML3; mastermind-like 3; Mastermind-like protein 3; mastermind-like transcriptional coactivator 3; polyglutamine rich; trinucleotide repeat containing 3
CAGH3; ERDA3; GDN; KIAA1816; MAM-2; MAM2; MAML3; TNRC3