Immunogen sequence: EVVEEHCASP EDKTLEVVSP SQSVTGSAGH TPYYQSPTDE KSSHLPTEVI EKPPAVPVSF EFSDAKDENE RASVSPMDEP VPDSESPIEK VLSPLRSPPL IGSESAYESF LSADDKASGR GAESPFEEKS GKQGSPDQVS PVSEMTST
MAP1b is the major microtubule associated protein in developing brain which changes its expression during development. In the newborn rat brain, it is a major component of microtubules but in the adult its level is ten-fold lower. This change in the level of expression occurs simultaneously with neuronal maturation. MAP1b is the first MAP to appear in growing axons during development as it is present from the first emergence of the nascent axon from the cell body.
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Protein Aliases: MAP-1B; MAP1 light chain LC1; MAP1B heavy chain; MAP5; Microtubule-associated protein 1B; PPP1R102; protein phosphatase 1, regulatory subunit 102
Gene Aliases: FUTSCH; MAP1B; MAP5; PPP1R102
UniProt ID: (Human) P46821
Entrez Gene ID: (Human) 4131