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Invitrogen
MAP1S Polyclonal Antibody
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FIGURE: 1 / 11
MAP1S Antibody (PA5-100607) in ICC/IF
Immunocytochemistry analysis of MAP1S in HepG2 cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with MAP1S polyclonal antibody (Product # PA5-100607) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L) (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG(H+L) (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).
Product Details
PA5-100607
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human MAP1S(Accession Q66K74), corresponding to amino acid residues S273-D323.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total MAP1S.
Target Information
Microtubule-associated protein that mediates aggregation of mitochondria resulting in cell death and genomic destruction (MAGD). Plays a role in anchoring the microtubule organizing center to the centrosomes. Binds to DNA. Plays a role in apoptosis. Involved in the formation of microtubule bundles.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BPY2 interacting protein 1; BPY2-interacting protein 1; MAP-1S; Microtubule-associated protein 1S; Microtubule-associated protein 8; OK/SW-cl.100; unnamed protein product; Variable charge Y chromosome 2-interacting protein 1; VCY2-interacting protein 1
Gene Aliases: 6430517J16Rik; BPY2IP1; C19orf5; MAP1S; MAP8; Mtap1s; VCY2IP-1; VCY2IP1
UniProt ID: (Human) Q66K74, (Rat) P0C5W1, (Mouse) Q8C052
Entrez Gene ID: (Human) 55201, (Rat) 290640, (Mouse) 270058
microtubule cytoskeleton organization
microtubule bundle formation
autophagy
apoptotic process
mitotic spindle organization
nervous system development
axonogenesis
brain development
dendrite development
regulation of microtubule depolymerization
microtubule anchoring at centrosome
mitochondrion transport along microtubule
neuron projection morphogenesis
metaphase plate congression
execution phase of apoptosis
regulation of chromatin disassembly
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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