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| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:1,000 | - |
ELISA (ELISA) |
1:10,000 | - |
Immunoprecipitation (IP) |
1:50-1:250 | - |
Dot blot (DB) |
1:10,000 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Synthetic peptide correpsonding to the C-terminal taken within amino acid region 900-950 on human MAP3K10 protein. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.5-1.5 mg/mL |
Purification |
Affinity chromatography |
Storage buffer |
proprietary buffer, pH 7.4-7.8, with 0.5% BSA, 30% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
MLK2 is a member of the serine/threonine kinase family. This kinase has been shown to activate MAPK8/JNK and MKK4/SEK1, and this kinase itself can bephoshorylated, and thus activated by JNK kinases. This kinase functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: MAP3K9; MEKK9; Mitogen-activated protein kinase kinase kinase 10; Mixed lineage kinase 2; mixed-lineage kinase 2; MKN28 derived nonreceptor_type; MKN28 derived nonreceptor_type serine/threonine kinase; MKN28 kinase; MLK1; PRKE1; Protein kinase MST; serine/threonine kinase
Gene Aliases: BC028668; BC046514; MAP3K10; MEKK10; MLK2; MST
UniProt ID: (Human) Q02779, (Rat) D3ZG83, (Mouse) Q66L42
Entrez Gene ID: (Human) 4294, (Rat) 308463, (Mouse) 269881
Molecular Function:
non-receptor serine/threonine protein kinase
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