This gene belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined; however, it has been shown to play a role in the regulation of embryonic and ocular development. Mutations in this gene cause various glaucoma phenotypes including primary congenital glaucoma, autosomal dominant iridogoniodysgenesis anomaly, and Axenfeld-Rieger anomaly.
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Protein Aliases: MAP 4; MAP-4; MAP4; Microtubule-associated protein 4
Gene Aliases: AA407148; MAP-4; MAP4; Mtap-4; Mtap4