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| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:600-1:2,000 | View 3 publications 3 publications |
Immunohistochemistry (IHC) |
- | View 3 publications 3 publications |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:50-1:500 | - |
Immunoprecipitation (IP) |
0.5-4.0 µg | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Published species |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
MAP4 Fusion Protein Ag1741 (629-979 aa encoded by BC012794) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.4 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.1% sodium azide |
Storage conditions |
-20°C |
Immunogen sequence: KSTQTVAKT TTAAAVASTG PSSRSPSTLL PKKPTAIKTE GKPAEVKKMT AKSVPADLSR PKSTSTSSMK KTTTLSGTAP AAGVVPSRVK ATPMPSRPST TPFIDKKPTS AKPSSTTPRL SRLATNTSAP DLKNVRSKVG STENIKHQPG GGRAKVEKKT EAAATTRKPE SNAVTKTAGP IASAQKQPAG KVQIVSKKVS YSHIQSKCGS KDNIKHVPGG GNVQIQNKKV DISKVSSKCG SKANIKHKPG GGDVKIESQK LNFKEKAQAK VGSLDNVGHL PAGGAVKTEG GGSEAPLCPG PPAGEEPAIS EAAPEAGAPT SASGLNGHPT LSGGGDQREA QTLDSQIQET SI (629-979 aa encoded by BC012794)
The protein encoded by this gene is a major non-neuronal microtubule-associated protein. This protein contains a domain similar to the microtubule-binding domains of neuronal microtubule-associated protein (MAP2) and microtubule-associated protein tau (MAPT/TAU). This protein promotes microtubule assembly, and has been shown to counteract destabilization of interphase microtubule catastrophe promotion. Cyclin B was found to interact with this protein, which targets cell division cycle 2 (CDC2) kinase to microtubules. The phosphorylation of this protein affects microtubule properties and cell cycle progression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: MAP 4; MAP-4; Microtubule-associated protein 4
Gene Aliases: AA407148; MAP-4; MAP4; Mtap-4; Mtap4
UniProt ID: (Human) P27816, (Mouse) Q7TPD4, (Rat) Q5M7W5
Entrez Gene ID: (Human) 4134, (Mouse) 17758, (Rat) 367171
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