This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
Immunogen sequence: PPAQALEIMM GLKTTDMAPS KETEMALAKD MALATKTEVA LAKDMESPTK LDVTLAKDMQ PSMESDMALV KDMELPTEKE VALVKDVRWP TETDVSSAKN VV
Highest antigen sequence identity to the following orthologs: Mouse - 48%, Rat - 47%.
The protein encoded by this gene is a major non-neuronal microtubule-associated protein. This protein contains a domain similar to the microtubule-binding domains of neuronal microtubule-associated protein (MAP2) and microtubule-associated protein tau (MAPT/TAU). This protein promotes microtubule assembly, and has been shown to counteract destabilization of interphase microtubule catastrophe promotion. Cyclin B was found to interact with this protein, which targets cell division cycle 2 (CDC2) kinase to microtubules. The phosphorylation of this protein affects microtubule properties and cell cycle progression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: MAP-4; Microtubule-associated protein 4
Gene Aliases: MAP4
UniProt ID: (Human) P27816
Entrez Gene ID: (Human) 4134