The protein encoded by this gene shares significant homology to the adenomatous polyposis coli (APC) protein-binding EB1 gene family. The function of this protein is unknown; however, its homology suggests involvement in tumorigenesis of colorectal cancers and proliferative control of normal cells. This gene may belong to the intermediate/early gene family, involved in the signal transduction cascade downstream of the TCR. Alternative splicing results in multiple transcript variants.
Protein Aliases: APC-binding protein EB1; APC-binding protein EB2; EB2; End-binding protein 2; Microtubule-associated protein RP/EB family member 2; T-cell activation protein, EB1 family; T-cell activation protein, EB1 family, member 2
Gene Aliases: AI314113; C820009F03Rik; CSCSC2; D18Abb1e; EB1; EB2; MAPRE2; RP1
Molecular Function: non-motor microtubule binding protein