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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 1 and 186 of Human MARCH5|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 1% BSA, 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-31190 targets MARCH5 in IF and WB applications and shows reactivity with Human samples.
The PA5-31190 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 186 of Human MARCH5.
MARCH5 is a ubiquitin ligase of the mitochondrial outer membrane that plays a role in the control of mitochondrial morphology by regulating mitofusin-2 (MFN2; MIM 608507) and DRP1 (DNM1L; MIM 603850) (Nakamura et al., 2006 [PubMed 16936636]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
MARCH-V; membrane associated ring finger 5; membrane-associated ring finger (C3HC4) 5; membrane-associated RING finger protein 5; membrane-associated RING-CH protein V; mitochondrial ubiquitin ligase; MITOL; ring finger protein 153; RNF153
MARCH-V; MARCH5; MITOL; RNF153