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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • MARK3 Antibodies

          Invitrogen

          MARK3 Polyclonal Antibody

          1 Reference
          View all (31) MARK3 antibodies

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          Cite MARK3 Polyclonal Antibody

          • Antibody Testing Data (2)
          MARK3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          MARK3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 2

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          MARK3 Antibody (PA5-29328) in IHC (P)

          Immunohistochemical analysis of paraffin-embedded human colon carcinoma, using Mark3 (Product # PA5-29328) antibody at 1:500 dilution. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          MARK3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          MARK3 Antibody in Western Blot (WB)

          Product Details

          PA5-29328

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:3,000
          -

          Immunohistochemistry (IHC)

          -
          View 1 publication 1 publication

          Immunohistochemistry (Paraffin) (IHC (P))

          1:100-1:1,000
          -
          Product Specifications

          Species Reactivity

          Human

          Published species

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein encompassing a sequence within the center region of human Mark3. The exact sequence is proprietary.

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.99 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          0.1M tris glycine, pH 7, with 20% glycerol

          Contains

          0.01% thimerosal

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2546804

          Product Specific Information

          Recommended positive controls: HCT116.

          Predicted reactivity: Mouse (94%), Xenopus laevis (83%).

          Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

          Target Information

          MARK3 is a member of a group of kinases known to regulate cell polarity via phosphorylation of microtubule-associated proteins (MAPs). The protein encoded by MARK3 is activated by phosphorylation and in turn is involved in the phosphorylation of tau proteins MAP2 and MAP4. Several transcript variants encoding different isoforms have been found for MARK3.

          ⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: C-TAK1; Cdc25C-associated protein kinase 1; cTAK1; ELKL motif kinase 2; EMK-2; MAP/microtubule affinity-regulating kinase 3; Par-1a; Protein kinase STK10; Ser/Thr protein kinase PAR-1; Serine/threonine-protein kinase p78

          View more View less

          Gene Aliases: CTAK1; EMK2; KP78; MARK3; Par-1a; PAR1A

          View more View less

          UniProt ID: (Human) P27448

          View more View less

          Entrez Gene ID: (Human) 4140

          View more View less

          Function(s)
          protein serine/threonine kinase activity protein binding ATP binding non-receptor serine/threonine protein kinase
          Process(es)
          MAPK cascade microtubule cytoskeleton organization establishment of cell polarity
          It has to be done as per old AB suggested Products section.
          guarantee_icon

          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

          Learn more
          help_icon

          We're here to help

          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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