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Product Details
10426-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Not Applicable
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
MAX Fusion Protein Ag0680 (1-151 aa encoded by BC003525)
Conjugate
Form
Liquid
Concentration
0.37 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Bands recognized by this antibody are much larger than predicted.^M
^M
Immunogen sequence: MSDNDDIEV ESDADKRAHH NALERKRRDH IKDSFHSLRD SVPSLQGEKA SRAQILDKAT EYIQYMRRKN HTHQQDIDDL KRQNALLEQQ VRALEKARSS AQLQTNYPSS DNSLYTNAKG STISAFDGGS DSSSESEPEE PQSRKKLRME AS (1-151 aa encoded by BC003525)
Target Information
The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Multiple alternatively spliced transcript variants have been described for this gene but the full-length nature for some of them is unknown.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: bHLHd4; Class D basic helix-loop-helix protein 4; Delta-Max; MGC10775; MGC11225; MGC18164; MGC34679; MGC36767; Myc-associated factor X; Myc-binding novel HLH/LZ protein; orf1; Protein max; Protein myn
Gene Aliases: AA960152; AI875693; BHLHD4; bHLHd5; bHLHd6; bHLHd7; bHLHd8; MAX; Myn
UniProt ID: (Human) P61244, (Mouse) P28574
Entrez Gene ID: (Human) 4149, (Mouse) 17187
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcription factor activity, RNA polymerase II core promoter sequence-specific
transcription factor activity, sequence-specific DNA binding
transcription cofactor activity
transcription coactivator activity
protein binding
protein complex binding
protein homodimerization activity
protein heterodimerization activity
DNA binding
sequence-specific DNA binding
protein dimerization activity
basic helix-loop-helix transcription factor
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
protein complex assembly
cellular response to starvation
negative regulation of gene expression
response to insulin
response to axon injury
neuron apoptotic process
retina development in camera-type eye
cellular response to peptide hormone stimulus
transcription, DNA-templated
regulation of transcription, DNA-templated
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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