This target displays homology in the following species: Cow: 86%; Dog: 93%; Guinea Pig: 86%; Horse: 86%; Human: 100%; Mouse: 86%; Rabbit: 86%; Rat: 86%
Acyltransferase which mediates the conversion of lysophosphatidylethanolamine (1-acyl-sn-glycero-3- phosphoethanolamine or LPE) into phosphatidylethanolamine (1,2- diacyl-sn-glycero-3-phosphoethanolamine or PE) (LPEAT activity). Catalyzes also the acylation of lysophosphatidic acid (LPA) into phosphatidic acid (PA) (LPAAT activity). Has also a very weak lysophosphatidylcholine acyltransferase (LPCAT activity). Prefers oleoyl-CoA as the acyl donor. Lysophospholipid acyltransferases (LPLATs) catalyze the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle.
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Protein Aliases: 1-acylglycerophosphate O-acyltransferase; 1-acylglycerophosphocholine O-acyltransferase; 1-acylglycerophosphoethanolamine O-acyltransferase; 231-; 231n7; LPAAT; LPC acyltransferase 4; LPCAT; LPEAT; LPLAT 2; Lyso-PA acyltransferase; Lyso-PC acyltransferase 4; Lyso-PE acyltransferase; Lysophosphatidic acid acyltransferase; Lysophosphatidylcholine acyltransferase; Lysophosphatidylcholine acyltransferase 4; Lysophosphatidylethanolamine acyltransferase; Lysophospholipid acyltransferase 2; MBOAT2; membrane bound O-acyltransferase domain containing 2; Membrane-bound O-acyltransferase domain-containing protein 2; mLPCAT4; O-acyltransferase (membrane bound) domain containing 2; O-acyltransferase domain-containing protein 2; OACT2
Gene Aliases: 2810049G06Rik; AU022889; AW547221; LPAAT; LPCAT4; LPEAT; LPLAT 2; MBOAT2; Moact2; OACT2