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          • Primary Antibodies ›
          • MCCC1 Antibodies

          Invitrogen

          MCCC1 Polyclonal Antibody

          View all (9) MCCC1 antibodies

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          Cite MCCC1 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (4)
          MCCC1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.
          MCCC1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 4

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          MCCC1 Antibody (PA5-87569) in IHC (P)

          Immunohistochemistry analysis of MCCC1 in paraffin-embedded mouse kidney. Samples were incubated with MCCC1 Polyclonal antibody (Product # PA5-87569) using a dilution of 1:100 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          PMID: {{$ctrl.currentElement.benchSciPubmedId}}
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          MCCC1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          MCCC1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          MCCC1 Antibody in Western Blot (WB)
          MCCC1 Antibody in Western Blot (WB)
          MCCC1 Polyclonal Antibody

          Product Details

          PA5-87569

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:1,000-1:5,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:100
          -

          ELISA (ELISA)

          1 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant fusion protein containing a sequence corresponding to amino acids 640-725 of human MCCC1 (NP_0645513)
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.57 mg/mL

          Amount

          57 µg

          Purification

          Affinity Chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.05% ProClin 300

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2804260

          Product Specific Information

          Positive Samples: Jurkat, Mouse kidney; Cellular Location: Mitochondrion matrix

          Immunogen sequence: VSSQETQGGP LAPMTGTIEK VFVKAGDKVK AGDSLMVMIA MKMEHTIKSP KDGTVKKVFY REGAQANRHT PLVEFEEEES DKRESE

          Target Information

          MCCC1 is the large subunit of3-methylcrotonyl-CoA carboxylase. This enzyme functions as aheterodimer and catalyzes the carboxylation of 3-methylcrotonyl-CoAto form 3-methylglutaconyl-CoA.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: 3-methylcrotonyl-CoA carboxylase 1; 3-methylcrotonyl-CoA carboxylase 1 {ECO:0000250|UniProtKB:Q96RQ3}; 3-methylcrotonyl-CoA carboxylase biotin-containing subunit; 3-methylcrotonyl-CoA carboxylase biotin-containing subunit {ECO:0000250|UniProtKB:Q96RQ3}; 3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha; 3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha {ECO:0000250|UniProtKB:Q96RQ3}; biotin carboxylase; biotin-dependent carboxylase; MCCA; subunit A; MCCase subunit alpha; MCCase subunit alpha {ECO:0000250|UniProtKB:Q96RQ3}; mccc1 {ECO:0000312|EMBL:AAH88473.1, ECO:0000312|RGD:1310615}; methylcrotonoyl-CoA carboxylase 1 (alpha); methylcrotonoyl-CoA carboxylase 1 (alpha) isoform MCCC1_1; methylcrotonoyl-CoA carboxylase 1 (alpha) isoform MCCC1_2; methylcrotonoyl-CoA carboxylase alpha; Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial; methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial {ECO:0000250|UniProtKB:Q96RQ3}; methylcrotonoyl-Coenzy; methylcrotonoyl-Coenzyme A carboxylase 1 (alpha); unnamed protein product

          View more View less

          Gene Aliases: 1810045E08Rik; 2310058B18Rik; MCC-B; MCCA; MCCalpha; MCCC1; MCCCalpha; R75106

          View more View less

          UniProt ID: (Human) Q96RQ3, (Rat) Q5I0C3, (Mouse) Q99MR8

          View more View less

          Entrez Gene ID: (Human) 56922, (Rat) 294972, (Mouse) 72039

          View more View less

          Function(s)
          nucleotide binding biotin carboxylase activity methylcrotonoyl-CoA carboxylase activity protein binding ATP binding biotin binding ligase activity metal ion binding catalytic activity ligase
          Process(es)
          leucine catabolic process biotin metabolic process branched-chain amino acid catabolic process metabolic process
          It has to be done as per old AB suggested Products section.

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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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