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.jpg "MCCC2 Antibody (MA5-22463) in IHC (PFA)")
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1-5 µg/mL | - |
Immunohistochemistry (PFA fixed) (IHC (PFA)) |
3 µg/mL | - |
ELISA (ELISA) |
Assay-Dependent | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human |
Host/Isotype |
Mouse / IgG1, kappa |
Class |
Monoclonal |
Type |
Antibody |
Clone |
2B3 |
Immunogen |
MCCC2 (NP_071415, 456 a.a. ~ 563 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.5 mg/mL |
Purification |
Affinity chromatography |
Storage buffer |
PBS, pH 7.4 |
Contains |
no preservative |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2577192 |
Peptide Sequence: AYSPRFLYIW PNARISVMGG EQAANVLATI TKDQRAREGK QFSSADEAAL KEPIIKKFEE EGNPYYSSAR VWDDGIIDPA DTRLVLGLSF SAALNAPIEK TDFGIFRM
COX3 is a multi-pass membrane protein. It belongs to the cytochrome c oxidase subunit 3 family. Defects in COX3 are a cause of Leber hereditary optic neuropathy (LHON) and cytochrome c oxidase deficiency (COX deficiency). Defects in MT-CO3 are also found in mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes (MELAS) syndrome and recurrent myoglobinuria.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 3-methylcrotonyl-CoA carboxylase 2; 3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit; 3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta; biotin carboxylase; MCCase subunit beta; meth; methylcrotonoyl-CoA carboxylase 2 (beta); Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial; methylcrotonoyl-Coenzyme A carboxylase 2 (beta); non-biotin containing subunit of 3-methylcrotonyl-CoA carboxylase; testicular secretory protein Li 29
Gene Aliases: MCCB; MCCC2
UniProt ID: (Human) Q9HCC0
Entrez Gene ID: (Human) 64087
Molecular Function:
ligase
metabolite interconversion enzyme
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