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Product Details
PA5-100662
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human MCF2L(Accession O15068), corresponding to amino acid residues V295-Q345.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2850166
Product Specific Information
Antibody detects endogenous levels of total MCF2L.
Target Information
This gene encodes a guanine nucleotide exchange factor that interacts specifically with the GTP-bound Rac1 and plays a role in the Rho/Rac signaling pathways. A variant in this gene was associated with osteoarthritis. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DBL's big sister; FLJ12122; Guanine nucleotide exchange factor DBS; mcf.2 transforming sequence-like; MCF2 transforming sequence-like protein; MCF2-transforming sequence-like protein; OST oncogene; RP11-98F14.2
Gene Aliases: ARHGEF14; DBS; KIAA0362; mcf 2l; MCF2L; OST
UniProt ID: (Human) O15068
Entrez Gene ID: (Human) 23263, (Rat) 117020
regulation of Rho protein signal transduction
intracellular signal transduction
positive regulation of apoptotic process
positive regulation of GTPase activity
regulation of small GTPase mediated signal transduction
Rho protein signal transduction
positive regulation of transcription from RNA polymerase II promoter
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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