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          Disclaimer

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • MCM2 Antibodies

          Active Motif

          MCM2 Polyclonal Antibody

          View all (59) MCM2 antibodies

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          Cite MCM2 Polyclonal Antibody

          • Antibody Testing Data (1)
          MCM2 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.
          MCM2 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          MCM2 Antibody (61717) in WB

          MCM2 antibody (pAb) tested by Western blot. MCM2 detection by Western blot. The analysis was performed using MCF7 nuclear cell extract (20 µg) and MCM2 antibody at a 1:1,000 dilution. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          MCM2 Antibody in Western Blot (WB)
          MCM2 Polyclonal Antibody

          Product Details

          61717

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:1,000
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          This antibody was raised against a full-length recombinant protein corresponding to human MCM2.
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          Conc. Not Determined

          Purification

          Antigen affinity chromatography, Affinity chromatography

          Storage buffer

          PBS, pH 7.5, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2636824

          Target Information

          MCM2 (Mini chromosome maintenance protein 2) is involved in regulating DNA replication. MCM2 (also called CDCL1, mitotin and BM28), is a human nuclear protein that is crucial in the cell cycle, being involved in the onset of DNA replication and cell division. It is similar to members of the family of early S-phase proteins. MCM2 has been mapped to 3q21. From its localization, CDCL1 became a candidate for an oncogene affected by chromosomal breaks in acute myeloid leukemia (AML).

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: cell devision cycle-like 1; cyclin-like 1; DNA replication licensing factor MCM2; MGC10606; minichromosome maintenance deficient 2 (mitotin); Minichromosome maintenance protein 2 homolog; Nuclear protein BM28

          View more View less

          Gene Aliases: BM28; CCNL1; cdc19; CDCL1; D3S3194; DFNA70; KIAA0030; MCM2; MITOTIN

          View more View less

          UniProt ID: (Human) P49736

          View more View less

          Entrez Gene ID: (Human) 4171

          View more View less

          Function(s)
          DNA binding DNA helicase activity DNA replication origin binding protein binding ATP binding enzyme binding histone binding metal ion binding DNA metabolism protein
          Process(es)
          G1/S transition of mitotic cell cycle DNA replication DNA unwinding involved in DNA replication DNA replication initiation nucleosome assembly cell cycle cellular response to interleukin-4
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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