Search
Invitrogen
MCM9 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
FIGURE: 1 / 1
MCM9 Antibody (PA5-49293) in WB
Western blot analysis of MCM9 in various lysates. Samples were incubated with MCM9 polyclonal antibody (Product # PA5-49293) using a dilution of 1:1,000 followed by Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at a dilution of 1:10,000. Lysates/proteins: 20 µg per lane. Lane 1: 293 whole cell lysate; Lane 2: K562 whole cell lysate. Predicted band size: 127 kDa. Blocking/Dilution buffer: 5% NFDM/TBST.
Product Details
PA5-49293
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 316-345 amino acids from the C-terminal region of human MCM9.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
200 µg
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Predicted to react with bovine based on sequence homology.
Target Information
Component of the MCM8-MCM9 complex, a complex involved in homologous recombination repair following DNA interstrand cross-links and plays a key role during gametogenesis. The MCM8- MCM9 complex probably acts as a hexameric helicase downstream of the Fanconi anemia proteins BRCA2 and RAD51 and is required to process aberrant forks into homologous recombination substrates and to orchestrate homologous recombination with resection, fork stabilization and fork restart.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: DNA 3'-5' helicase MCM9; DNA helicase MCM9; DNA replication licensing factor MCM9; hMCM9; Mini-chromosome maintenance deficient domain-containing protein 1; Minichromosome maintenance 9; minichromosome maintenance complex component 9; unnamed protein product
Gene Aliases: C6orf61; dJ329L24.1; dJ329L24.3; MCM9; MCMDC1; ODG4
UniProt ID: (Human) Q9NXL9
Entrez Gene ID: (Human) 254394
nucleotide binding
DNA binding
DNA helicase activity
chromatin binding
single-stranded DNA binding
helicase activity
protein binding
ATP binding
hydrolase activity
ATPase activity
single-stranded DNA-dependent ATP-dependent DNA helicase activity
enzyme binding
MutLbeta complex binding
MutSalpha complex binding
MutSbeta complex binding
macromolecular complex binding
double-strand break repair via homologous recombination
DNA replication
DNA repair
cellular response to DNA damage stimulus
gamete generation
female gamete generation
recombinational interstrand cross-link repair
mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication
protein localization to chromatin
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support