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Proteintech
MCT4 Polyclonal Antibody
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Product Details
22787-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Published species
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
MCT4 Fusion Protein Ag18788 (402-465 aa encoded by BC112269)
Conjugate
Form
Liquid
Concentration
0.38 mg/mL
Amount
57 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: LLLGNFFCI RKKPKEPQPE VAAAEEEKLH KPPADSGVDL REVEHFLKAE PEKNGEVVHT PETSV (402-465 aa encoded by BC112269)
Target Information
Lactic acid and pyruvate transport across plasma membranes is catalyzed by members of the proton-linked monocarboxylate transporter (MCT) family, which has been designated solute carrier family-16. Each MCT appears to have slightly different substrate and inhibitor specificities and transport kinetics, which are related to the metabolic requirements of the tissues in which it is found. The MCTs, which include MCT1 (SLC16A1; MIM 600682) and MCT2 (SLC16A7; MIM 603654), are characterized by 12 predicted transmembrane domains (Price et al., 1998 [PubMed 9425115]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: MCT 3; MCT 4; MGC138472; MGC138474; monocarboxylate transporter; Monocarboxylate transporter 3; Monocarboxylate transporter 4; MOT4; solute carrier family 16 (monocarboxylate transporter), member 3; solute carrier family 16 (monocarboxylic acid transporters), member 3; Solute carrier family 16 member 3; solute carrier family 16, member 3 (monocarboxylic acid transporter 4); unnamed protein product
Gene Aliases: MCT 3; MCT 4; MCT-3; MCT-4; MCT3; MCT4; SLC16A3
UniProt ID: (Human) O15427, (Rat) O35910
Entrez Gene ID: (Human) 9123, (Rat) 80878
RNA binding
protein binding
monocarboxylic acid transmembrane transporter activity
lactate transmembrane transporter activity
symporter activity
lactate:proton symporter activity
transmembrane transporter activity
pyruvate transmembrane transporter activity
secondary active monocarboxylate transmembrane transporter activity
poly(A) RNA binding
transporter
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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