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|Tested species reactivity||Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant full length protein (Mouse).|
|Contains||0.1% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-22530 detects MDC in Mouse and Rat samples.
PA1-22530 has been successfully used in Western Blot procedures.
PA1-22530 immunogen corresponds to Recombinant full length protein (Mouse)..
MDC (macrophage-derived chemokine) is a 69-amino acid CC chemokine with a NH2-terminalsequence of 24 residues as a signal sequence. It was originally cloned from human monocyte-derived macrophages (ref 1). Recombinant MDC attracts monocyte-derived dendritic cells, activated lymphocytes and natural killer cells. MDC has anti-HIV-1 activity (ref 2). Expression of MDC mRNA in macrophages is enhanced by LPS, IL-1 and TNF. MDC is a functional ligand for CCR4 (ref 4).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Activated B and dendritic cell-derived; AW060611; C-C motif chemokine 22; CC chemokine ABCD-1; dendritic cell and B cell derived chemokine; Mdc; RP24-69A20.1; small inducible cytokine A22; SMALL INDUCIBLE CYTOKINE A22 PRECURSOR (CC CHEMOKINE ABCD-1) (ACTIVATED B AND DENDRITIC CELL-DERIVED); small inducible cytokine subfamily A (Cys-Cys) member 22; small inducible cytokine subfamily A (Cys-Cys), member 22; small inducible cytokine subfamily A, member 22; small inducible cytokine subfamily A22; Small-inducible cytokine A22
ABCD-1; Abcd1; Ccl22; DCBCK; MDC; Scya22